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OneFlowSBI One Model, Many Queries for Simulation-Based Inference

M Nautiyal, L Ju, M Ernfors, K Hagland… - arXiv preprint arXiv …, 2026 - arxiv.org
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… This paper introduces a unified simulation based inference method that supports multiple inference queries across scientific and engineering applications. As with any SBI …

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BibTeX

@article{2601.22951v1,
Author = {Mayank Nautiyal and Li Ju and Melker Ernfors and Klara Hagland and Ville Holma and Maximilian Werkö Söderholm and Andreas Hellander and Prashant Singh},
Title = {OneFlowSBI: One Model, Many Queries for Simulation-Based Inference},
Eprint = {2601.22951v1},
ArchivePrefix = {arXiv},
PrimaryClass = {stat.ML},
Abstract = {We introduce \textit{OneFlowSBI}, a unified framework for simulation-based inference that learns a single flow-matching generative model over the joint distribution of parameters and observations. Leveraging a query-aware masking distribution during training, the same model supports multiple inference tasks, including posterior sampling, likelihood estimation, and arbitrary conditional distributions, without task-specific retraining. We evaluate \textit{OneFlowSBI} on ten benchmark inference problems and two high-dimensional real-world inverse problems across multiple simulation budgets. \textit{OneFlowSBI} is shown to deliver competitive performance against state-of-the-art generalized inference solvers and specialized posterior estimators, while enabling efficient sampling with few ODE integration steps and remaining robust under noisy and partially observed data.},
Year = {2026},
Month = {Jan},
Url = {http://arxiv.org/abs/2601.22951v1},
File = {2601.22951v1.pdf}
}

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