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A statistical framework for the analysis of multivariate infectious disease surveillance counts
L Held, M Höhle, M Hofmann - Statistical modelling, 2005 - journals.sagepub.com
… the proposed model framework is easily estimated by ML using generic optimization routines, for example, the function optim() in R, so there is no need for simulation-based inference …
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… the proposed model framework is easily estimated by ML using generic optimization routines, for example, the function optim() in R, so there is no need for simulation-based inference …