Segmental copy number amplifications are more stable than aneuploidies in the absence of selection
T De, N Ben Nun, P Spealman, I Suresh… - Molecular Biology …, 2026 - academic.oup.com
… Using simulation-based inference to estimate reversion 29 rates and fitness effects, we determined negative selection as the primary driver of CNV loss. 30 Whole-genome …
Link to paper
… Using simulation-based inference to estimate reversion 29 rates and fitness effects, we determined negative selection as the primary driver of CNV loss. 30 Whole-genome …