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Segmental copy number amplifications are more stable than aneuploidies in the absence of selection

T De, N Ben Nun, P Spealman, I Suresh… - Molecular Biology …, 2026 - academic.oup.com
Genetics paper Suggest

… Using simulation-based inference to estimate reversion 29 rates and fitness effects, we determined negative selection as the primary driver of CNV loss. 30 Whole-genome …

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